Age Spots and Warning Signs of Skin Cancer

What is that Spot?

As time goes on, we start to notice brown spots and freckles — “souvenirs of Florida” — on the backs of our hands and on other sun exposed areas like the upper chest and face. At first these brown spots are small and light colored, but eventually they become a cosmetic problem — an obvious sign of premature aging of the skin because of ultraviolet damage from sun exposure or from tanning beds. (Learn more about Sun Damage)

By using modern high-SPF sunscreens like Ombrelle-60™ or Anthelios-60™ we can safely enjoy outdoor activities like gardening, golf and boating, and greatly reduce the rate at which our skin deteriorates. Patients who get into the habit of applying Retisol-A 0.01% cream (a prescription product which combines a retinoid and an SPF-15 sunscreen) to their faces every morning will usually see a considerable improvement in the appearance of their skin after 1-2 years, and if treatment is continued long-term patients will notice that their skin ages more slowly.

Hats and sun protective clothing can also slow down the rate at which “age spots” appear – and also reduce the chance that we will develop skin cancer. You can learn more about how to prevent sun damage, learn about the early warning signs of skin cancer and see photos of typical skin cancers at Skin Cancer Guide.ca.

The early warning signs of skin cancer include:

* new and unusual growths on the skin
* moles and freckles which have unusual colors or mixtures of colors
* moles and freckles with irregular borders
* growths on the skin which bleed, or which form an open sore which does not heal within a few weeks.

It is not too late for those of us who already have sun spots and age spots. I have seen many patients who had sun damage improve gradually over a period of 3-5 years simply in response to daily sun protection. For those who want more rapid and complete improvement in their sun damaged skin, one or two treatments with the Medlite™ laser can fade or eliminate brown “age spots” on the face, chest and hands within a few weeks.

Intense Pulsed Light (IPL) treatments, for example with the Cutera Xeo-600, can be used in cases where there is a background of tiny freckles and brown discoloration – sometimes erasing 20 years of irregular pigment with a series of 20 minute treatments! Where there is severe sun damage or when a person wishes the most rapid improvement (for example, if a daughter is getting married in two months) a medicine called Levulan™ is applied to the skin for one hour before treatment with the Cutera Xeo-600. Levulan™ is absorbed by cells in the skin which are misbehaving, and then is activated by light from the Xeo-600. The abnormal cells are shed from the skin over a period of 1-2 weeks, revealing fresher, healthier skin – and giving the patient a “fresh start”.

What ever the type of spot – if you have concerns, or if you see changes in its appearance, it is important that you have it inspected by your family physician or dermatologist.

Rejuvenating Face Lifts for Aging Skin

A Face Lift is a procedure that most people can benefit from. This may sound too radical but most people feel a need and desire to look their best. When skin creams and lotions, Botox, lasers, chemical peels and fillers fail - face lift may offer the solution that is difficult to resist. Of course, many people are afraid of having surgery and having a “surgical look” but fortunately face lifting techniques have evolved considerably to offer patients less invasive methods that even the most sophisticated patient can find attractive.

How The Technique Is Performed:

Face lift remains one of the most effective rejuvenating methods for the aging face. Its technique varies from simple skin excision to complex procedure including the repositioning of muscles, fat and skin. Recent trends in patients desires of having effective facial improvement while minimizing down-time have led to the development of newer, less traumatic, short scar, less recovery methods. Full understanding of the face and neck anatomy as well as the changes associated with aging process is required by the physician prior to undertaking any face lift procedure.

Two key subcutaneous structures are at the core of face-lift surgery - superficial musculoaponeurotic system (SMAS) and platysma. SMAS is a fibrous interlocking, sometimes ill-defined, structure/sheath deep to the skin fat. It extends from platysma muscle (a thin, fan-like muscle that extends from both collar bones to the jaw line) and reaches cheekbones as well as temple and scalp components. These two structures are utilized and modified in most face lift procedures.

As we age, several facial components undergo significant changes. The skin becomes less elastic that is associated with decrease in collagen support. Furthermore, there is modification of the facial fat with respect to its amount and position. In addition, there is remodeling of facial bones that in combination with fat and skin changes lead to aged facial appearance.

Most of the surgical face lifts procedures today are a variation of two-plane face lift - use of the epidermal-dermal component (full thickness skin) as well as the SMAS-platysma component. Optimal results require modification of SMAS-platysma component through resection, placation and/or suspension. It is this modification that is at the core of most face-lifts. These adjusted deep supporting structures provide durable framework over which skin can be safely re-draped. It is imperative to realize that stretching skin alone will not result in any sustained improvement and can lead to skin death, appearance of “surgical look” as well as significant facial distortion and scarring.

The Latest Techniques:

Latest face lift techniques utilize shorter skin incisions and are primarily designed for patients with mild to moderate jowls and neck laxity. With the recent advancements in local anesthetic and, in particular, the development of tumescent anesthesia, most face lift procedures can be safely and comfortably accomplished without the need for the traditional general anesthesia. These modified procedures have accomplished several things. Shorter incisions and local anesthetic make the recovery from modern face lifts much easier than in the past. In addition, the shorter scar and resulting less significant distortion of hairline make these methods much more appealing for modern men and women.

What Every Patient Needs To Do

As with any aesthetic procedure, pre-operative consultation is an optimal time for defining patient’s motivation for aesthetic improvement and developing plan of action. It is at this time that patient’s desires and fears can be explored. It is important for the patient to ask pertinent questions regarding the expected degree of sustained facial rejuvenation, the length of the scar as well as modification of the temporal and post-auricular hairline. With proper patient selection and optimization of desired procedure, most patients can achieve rewarding sustained results that can benefit most if not all of us at some point in our life.

Chamomile Provides Natural Skin Healing

Chamomile (or camomile) is a common name for several daisy-like plants. The greeks named them “earth-apple-on the ground” for their apple-like scent. There are several varieties of Chamomile - each one used for slightly different purposes or intensities of properties. German or blue chamomile and Roman (English) chamomile, or the “garden” chamomile are the most commonly used.

These two types of chamomile are used for health conditions and are most commonly found in skin care or beauty products. While the two kinds are thought to have similar effects on the body, the German variety is more commonly used in the United States. Chamomile, is one of the oldest of all herbs, dating back to ancient Egyptians. It’s both a pretty flower and an ancient healer. Chamomile has been widely used for children and adults for thousands of years for a variety of health conditions.

Chamomile Provides Natural Skin Healing

Chamomile is an essential addition to the herbal first aid kit. It is a useful herb in many situations. It can relieve anxiety and calm someone down in the event of stress. It can also relieve gastrointestinal upset - after a big meal, or when stress doesn’t mix well with your meal. Chamomile is even an excellent herb to use as compresses for eye problems. Warm two tea bags with chamomile flowers to ease itchy eyes, especially when traveling to different parts of the country and you are not immune to the allergens in that area. It is also used topically for skin conditions and for mouth ulcers resulting from cancer treatment.

How It Is Used

The flowering tops of the chamomile plant are used to make teas, liquid extracts, capsules, or tablets. The herb can also be applied to the skin as a cream or an ointment, or used as a mouth rinse.

Chamomile in Skin Care Products

This versatile herb is also recognized as a natural healing treatment that helps rejuvenate the skin. There are many wonderful natural facial treatments on the market today that incorporate Chamomile as a key ingredient.

To make a quick and easy tea facial, simply apply a paste made from one teaspoon of fine cornmeal mixed with cooled tea to the face, let dry, then gently rub off.

This very gentle skin tonic is ideal to replenish and enrich dry or sensitive skin. Its bactericidal, anti-itching, and antiseptic properties help to refresh the skin and reduce swelling.

Making paste with extra-strong brew and using it as an external wash or part of a hot compress can also help soothe burns, skin rashes, and sores.

Chamomile has excellent anti-inflammatory properties. Chamomile contains an anti-inflammatory compound called alpha bisabolol which helps to soothe itchy, red skin. For this reason, Chamomile along with some other herbs and natural treatments has shown promise as skin treatments for eczema.

According to family physician Dr. Kristie Leong, “Chamomile has been used throughout history to treat various skin conditions and some studies have shown it works as effectively as low dose steroid creams without the side effects. Chamomile oil can be purchased at some health food stores. It needs to be diluted with a carrier oil such as almond oil or jojoba and can then be applied as a skin treatment for eczema. Bathing in warm water containing chamomile flowers may also help to soothe inflammation and itching. Simply make a bath bag using chamomile flowers and float it in a tub of warm bath water.”

For easing skin inflammations and acne, make a strong chamomile tea, and wipe the cooled liquid over your face each morning. This effective daily rinse tones and cleanses.

Essential Oil Usage

Both Roman and German chamomile have excellent calming properties, but Roman chamomile is more effective for irritation, impatience and feeling disagreeable, and has great value in treating PMS and other menstrual and menopausal problems, while German chamomile  is superbly effective on the skin, not only to sooth and calm, but to heal and for tissue regeneration.

Side Effects and Cautions

* There are reports of rare allergic reactions in people who have eaten or come into contact with chamomile products. Reactions include skin rashes, throat swelling, shortness of breath, and anaphylaxis (a life-threatening allergic reaction).
* People are more likely to experience allergic reactions to chamomile if they are allergic to related plants in the daisy family, which includes ragweed, chrysanthemums, marigolds, and daisies.
* Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This helps to ensure coordinated and safe care.

Anti-Oxidants And Sun Damaged Skin

Sun damage or photo damage produces both skin cancers as well as photo-aging. Photo-aging shows itself on the skin as wrinkling, scaling, dryness, and mottled pigmentation. Ultra-violet light is absorbed by skin, which in turn produces a photo-chemical reaction.

The UVA light is absorbed by both DNA as well as urocanic acid, the photo-chemical reaction produces oxidation of both DNA, nucleide acid, and protein, as well as lipids, this is known as oxidative damage. Anti-oxidants have been evolved to protect against, and reverse some of the damage produced by sunlight. An anti-oxidant mechanism is very advanced in plants that protect against the damage from sun exposure.

Oxidation:

Oxidation is produced by reactive oxygen molecules. The DNA absorbs ultra-violet light mostly in the UVB (290-320 manometres) range. This produces damage mainly within the epidermis. UVA (320-400 manometres) penetrates deeper into the skin and produces damage in the epidermis, the dermis as well as affecting blood vessels. The UVA has a much more oxidizing effect on cells.

The carcinogenic or cancer forming effects of ultra-violet B produce mutations within the DNA. This initiates tumours within the epidermis. The UVA promotes these tumours as it has much more oxidizing stress on the skin than UVB. It may as a result be more cytotoxic and immunosuppressive.

Sunscreens:

Sunscreens certainly protect against ultra-violet light, the sunburning spectrum is UVB and sunscreens are very effective. Ultra-violet A is the most difficult to protect against. It is important to realize that the SPF numbers are calculated with an amount of sunscreen on skin that exceeds what most of us put on our own skin.

The SPF is calculated with a quantity of 2mg. of sunscreen per centimetre2. Most people will put on about half to one quarter of this when used as sun protection. Unfortunately, low quantities of sunscreen of per centimtre2 will have minimal sun protective effects. Usually if 5mg. per cm.2 of sunscreen is applied to the skin, the sun protective factor is in the region of an SPF of 3.

Anti-Oxidants:

Anti-oxidants play a significant part in the protective and repair mechanisms within animals and plants. This can be achieved by anti-oxidants that are produced within the skin itself or by those consumed or applied from plants. The anti-oxidant effects can be divided into those that have their protection through enzymes, and those that tend to reduce the quantity of hydrogen peroxide as well as lipid hydroperoxides.

Topical Anti-Oxidants:

The use of topical anti-oxidants has certain requirements, these have to be stable as well as being cosmetically acceptable. It is clear that anti-oxidants have a photo-protective benefit. The physiological anti-oxidants include vitamin C, vitamin E, and ubiquinol. Vitamin C is water-soluble and is a free radical scavenger, it is required for collagen synthesis and may inhibit elastin formation in the dermis.

It may also reduce pigment synthesis, as well as enhance epidermal barrier function. For it to be active it must be present on the skin at a pH of 3.5 or lower in order to have an anti-oxidative effect. Vitamin E is different from vitamin C, in that it is lipid soluble, there is evidence that combining vitamin E and vitamin C may be of some benefit. Other anti-oxidants to be considered will be selenium as well as zinc.

Plant Anti-Oxidants:

Plants synthesize vitamin C, vitamin E and flavones, and polyphenolic compounds.

• Silymarin
• Soy isoflavones
• Tea
• Polyphenols

These are all potent plant anti-oxidants.

Silymarin:

This is a Milk Thistle extract, the main component in terms of anti-oxidants is silybyn. This prevents lipid peroxidase action. It also has been shown to inhibit tumour promotion in animals.

Soy isoflavones:

Soy has been connected with a reduction in cardiovascular disease, and in some incidents’ of breast cancer when taken by mouth in large quantities. It has a phytoestrogen effect, which can reduce menopausal symptoms. The isoflavones are genistein and gaidzein. The genistein has a collagen synthesis effect. It is also anti-cancer. It has been used both orally as well as topically.

The genistein is a powerful scavenger of peroxyl radicals. This has a significant reduction in lipid peroxidase activity. It has been shown to reduce redness in the skin of mice which are subject to ultra-violet A. It also has an anti-inflammatory effect. The use of this compound reduces the immune suppression effect of ultra-violet light.

Tea polyphenols:

Tea is fermented initially to green, and then to black tea. The drinking of black tea has been shown to reduce the frequency of squamous cell carcinomas. Work done with green tea both topically and taken orally, shows that it reduces the ability of ultra-violet to produce skin cancers and redness, particularly in animals. The possibility of combining tea, plus vitamin E, to work together as anti-oxidants is interesting.

Much more work needs to be done in order to establish how combining anti-oxidants with sunscreens will have a very beneficial effect on reducing sun damage to skin.

Light-Activated Therapy and Aging Skin

A study in the October issue of the Archives of Dermatology, supports that Photodynamic therapy appears to cause molecular-level changes in aging skin that increase collagen production and improve skin appearance, a U.S. study finds. Meaning, light-activated therapy seems to rejuvenate aging skin.

In photodynamic therapy, a light-activated medication is exposed to a light source. Photodynamic therapy for aesthetic treatments typically involves application of a topical medication, such as 5-aminolevulinic acid (5-ALA).

In this study, Dr. Jeffrey S. Orringer and colleagues at the University of Michigan Medical School in Ann Arbor, used photodynamic therapy to treat 25 people, aged 54 to 83, with sun-damaged skin on their forearms.

Prior to treatment, the patients’ degree of skin damage was rated, and tissue samples were taken from their forearms. A solution containing 5-ALA was applied to the damaged skin and left on for three hours. The skin was then cleaned and treated with a pulsed-dye laser. The patients were re-examined four to five times over the following six months.

Tissue samples showed that treatment resulted in a fivefold increase in levels of a protein called Ki67, believed to play an important role in the growth and development of new skin cells. In addition, there was a 1.4-fold increase in the thickness of the skin’s outer layer (epidermis) and higher levels of enzymes and other compounds associated with the production of collagen, the main structural protein in skin.

“Photodynamic therapy with the specific treatment regimen employed produces statistically significant quantitative cutaneous molecular changes [e.g., production of types I and III collagen] that are associated with improved appearance of the skin,” the researchers wrote.

The findings suggest that use of a photosensitive compound such as 5-ALA in combination with pulsed-dye laser therapy prompts more beneficial changes in skin than laser therapy alone.

“Although our molecular measurements cannot yet precisely predict clinical outcomes for a single given patient, taken together they are very much in keeping with the bulk of the clinical literature and thus lend substantial support to the conclusions reached by other researchers who have published purely clinically oriented work in this field,” the study authors concluded.

“We believe that the quantitative amount of dermal repair and regeneration induced by a specific therapeutic intervention very likely underlies the degree of clinical rejuvenation produced.” they wrote. “Thus, it is our hope that, with further development, our working molecular model may one day be used to predict the clinical value of new technologies in aesthetic dermatology.”