Anti-Inflammatory Herbal Skincare Ingredients

October 7, 2010 by admin · Leave a Comment 

Are you suffering from an over-abundance of chemicals in your skincare products? Read on….

If you suffer from acne, rosacea, redness or uneven skin tone you might want to pay attention to the ingredients in your skincare products. Inflammation, redness and even allergic reactions can be caused by an overabundance of chemicals in your facial products. Whenever possible, choose facial products that contain a majority of natural or organic ingredients.  Many of these herbs are used today in anti-aging and anti-acne products like facial masks and all forms of cleansers, toners and moisturizers. There is a plethora of herbs to choose from, the following are some of the most predominant and effective.
Chamomile — This very gentle herb is ideal to replenish and enrich dry or sensitive skin. It’s bactericidal, anti-itching, and antiseptic properties help to refresh the skin and reduce swelling.
Chamomile contains phenolic derivatives, which have an antiseptic and healing quality, which is most helpful in relieving skin congestion. These soften the skin, making it an effective ingredient in any anti-aging cosmetic product.
Chamomile is an ideal ingredient to be used in general skin care, and especially where inflammation may be present, such as in various skin problems, including acne, irritation and other forms of rashes and skin complaints, plus the fact that it promotes granulation and cell regeneration.
Comfrey— Comfrey is a sweet, cooling herb with expectorant, astringent, soothing and healing effects. It reduces inflammation and controls bleeding.  It contains allantoin (a chemical compound commonly used in lotions and creams) as well as high amounts of mucilage. It is a superb wound healing herb, but the pyrrolizidine alkaloids (PA) can be carcinogenic and also cause liver damage if ingested in large doses or too frequently.
Used externally for psoriasis, eczema, sores, varicose veins and skin ulcers, arthritis, sprains, bunions, hemorrhoids, sore breasts during lactation, and injuries, including fractures.  It is particularly effective in slow healing wounds and to help repair tissue damage. Comfrey is used to stimulate growth of new skin cells.
Lavender—Is a great multi-purpose herb. It’s a skin healer; it stimulates cell growth, reduces inflammation, prevents scarring and balances the production of natural sebum or oil.  It is antibacterial, antiviral, antiseptic, and anti-inflammatory.
Green tea —Very beneficial for sensitive skin types by reducing inflammation and irritation in the skin. Wrinkles, skin sag and other signs of aging have been shown to benefit from Green tea. Green tea gets is power from polyphenols – which are antioxidant and anti-inflammatory and help slow down signs of premature of aging.
Rosemary —Helps strengthen the capillaries and has a rejuvenating effect. It contains caffeic acid and rosemarinic acid - both are potent antioxidant and anti-inflammatory agents.  The antioxidants contained in rosemary also help to protect your body’s cells from damage by free radicals.
Marshmallow —Is a flowering plant and it’s extracts have traditionally been used on the skin to treat inflammation.  It’s an excellent therapy for skin rashes or eruptions. The rich, demulcent nature of marshmallow gives it soothing, moistening and calming properties on the skin.
Aloe vera —Stimulates cell renewal, has anti-bacterial and anti-fungal properties. The 20 amino acids it contains are the building blocks of cell tissue.  It is beneficial for skin eruptions and for the treatment of bruises and burns. It is also a cellular regenerator.
Beta Carotene —Dermatologists use beta-carotene for its ability to increase cell turn-over and regeneration in the outer layers of the skin, making it effective for diseases and skin conditions. Topical application of beta-carotene in retailed skin care products can enhance the appearance of the skin by restoring suppleness and adding a “glowing” pigment that seemingly evens out the skin tone. Beta-carotene’s antioxidant attributes, such as sun damage protection, are used to prevent the signs of aging in the skin.
Mint— Mint has significant rejuvenating properties. It is an anti-pruitic and antiseptic, natural cleanser, alleviates, itching, infection, and sooths rashes or inflammation. It is a great addition for anti-acne and natural anti-aging skin care.
It is always best to use the herbs in their most natural form; fresh, dried, pulverized or diluted in common carrier oil, like almond, jojoba or hazelnut oil. You can also find many herbal options in essential oils, but use these with caution. The first rule of essential oil skin care is don’t apply undiluted oils directly to skin. They are super-concentrated, and can cause allergies or chemical burns if used undiluted.

Anti Aging with Some Papaya and Peaches

September 11, 2010 by vivowriter · Leave a Comment 

fruitcat1-150x150 Anti Aging with Some Papaya and PeachesThere are innumerable anti aging formula offered in the beauty marts. You must have seen a pile of anti aging products stacked up nicely at a beauty shelf while browsing through a cosmetic store. There is a wave about anti aging formulated products in the market. Now, how easy would it be if you can make your own anti aging concoction at home?

When it comes to anti aging, there is no better a fruit than papaya. Papaya enzymes help to fight free body radicals that cause premature skin aging. Papaya is also a storehouse of beta carotene, Vitamin E and A which consequently help to fight the signs of aging. Not only does the fruit help in preventing the formation of wrinkles, it also helps in erasing age lines that have already developed. It is recommended that people who have an extremely wrinkled skin must use papaya facial pack at least once in a week. Consistent usage of papaya mask will help in erasing out facial lines.

Peach is another great anti aging fruit. The fruit is a good natural source of antioxidants. As a result, it helps to postpone the ugly signs of aging. Peach tree is a native China tree but nowadays the fruit is commercially grown everywhere. Being a rich stock house of potassium, magnesium, calcium and key vitamins, peach is an incredible anti aging agent. Dry peaches are highly rich in sulphur quantities. As such, those who are allergic to sulphur must stay away from dried peaches. Peach pulp may be used to apply all over the facial skin in order to get a taut skin. You may add lemon or rose water in the mixture to enhance its effectiveness.

So, you see there are great anti aging agents lying in your refrigerator! Go, try them!

Arrest Aging By Using An Anti Aging Facial Mask

August 28, 2010 by vivowriter · Leave a Comment 

000000148031 Arrest Aging By Using An Anti Aging Facial MaskAging is a constant and a natural process and it cannot be stopped it can only be slowed down.  Fine lines on and around the eyes and the corners of the mouth is the manifestation aging. As soon as these lines are visible people start to panic and look for solutions. There are many answers to the issue. One of them is anti aging facial mask which gives wondrous results. The stores are flooded with product related to anti aging amongst which anti aging facial mask is the most popular. Call by any name clay mask, exfoliating mask or by any other name, the basic work that they do is to tighten the skin.

Some are born with genes which keep them looking young for a longer period of time where as there are people who look very old early in their life. They can blame it all on the genes however; there are various other reasons which can be held responsible for aging. Some of the culprits are the sun, pollution, heat and dust, lifestyle and some habits. Most of these can be controlled to arrest further deterioration of the skin. Skin care has to be there right from the beginning. Before applying any anti aging facial mask cleansing of the face and neck has to be done. It would be good if one could sit in a steam bath. There are tones of organic anti aging facial masks that can be made at home. Once a mask is applied it is good to sit back and relax for a while. Remove the mask and follow the daily regime of toning and moisturizing.

Before any beauty product is bought it is good to recognize the skin type, tone and texture so that the correct mask is bought to achieve the desired results.

Facial Masks To Defy Aging!

June 19, 2010 by vivowriter · Leave a Comment 

anti-aging-creams-1-150x150 Facial Masks To Defy Aging!The anti aging industry is booming! The credit for this flourishing industry goes to all those people out there who want to defy aging. Almost every elderly seems to have been bitten by the anti aging bug. Everybody seems to have taken the challenge to fight aging.

There is not one formula for anti aging. There are countless such formulas that are floating around in the market. Application of anti aging facial masks is a promising way to delay aging. Anti aging facial masks may work on two principles. Either they work on drooping skin to make it look taut or they focus primarily on age lines.

Anti aging facial masks are readily available in the stores. Before buying you must take the pains to go through the constituents of the mask. Keep away from masks or for that matter any anti aging formula that contains alcohol, parabens, propylene glycol and mineral oil. All of them are supposed to cause skin cancers. Omega 3 fatty acids, on the contrary are effective in battling aging.

Anti aging facial masks can be made at home with ease. Peach especially is known to defy aging. There are various other items available in every home that can be used to fight the signs of aging.

For those who do not want the ugly signs of aging to show up soon, there are a couple of points to be borne in mind. Sunlight is essential for the body. Excessive exposure to sun however, may cause pigmentation. It is also held that excessive exposure to sunlight causes wrinkles around the eyes. So it is important that you wear sun-shades whenever you go out in the sun. Also, you must always wear a sunscreen to protect your sun exposed skin. Sleeping upside down may also cause wrinkles. So, check on your sleeping posture.

Popular Herbs Used in Skin Care and Their Benefits

February 25, 2010 by admin · Leave a Comment 

Popular Herbs Used in Skin Care and Their Benefits: Chamomile, Aloe Vera, Lavender and Rosemary

Today skin care and cosmetics are increasingly going natural. You may have heard that herbs and oils are commonly used in skin care and cosmetics; but, you may not know why or what purpose they serve. why, and what do the do? Four very common and popular herbs that are used in the form of oil or gels are chamomile, Aloe Vera, lavender, and rosemary. All provide unique benefits for the skin and body.

The benefits of chamomile for the skin and body range from calming effects to healing. Recent and on-going research has identified chamomile’s

chamomile herb

chamomile herb

specific benefits as anti-inflammatory, anti-bacterial and anti-allergenic. Chamomile is most often recognized as an herbal tea; however, chamomile is present in many skin care products. Chamomile’s active ingredients extracted from the flower are essential oils and flavonoids. Essential oils help to calm and relax irritated skin. Essential oils have also been found to be beneficial to treat and sooth acne prone skin. Flavonoids – or plant metabolites- are rich in anti oxidants that help the body repair and heal damaged skin, as well as fight free radicals, which create damage to bodily cells. Chamomile has few side effects and is effective and beneficial to the skin topically or if ingested.

Aloe Vera contains numerous, minerals, vitamin, enzymes, and natural sugars that help with inflammation. Aloe Vera is commonly known for its healing properties, which explains its popular use in skin care. Aloe Vera aids in the healing of skin burns and cuts and moisturizes and softens skin. Aloe Vera is used in skin care products to help with dry sensitive skin as the plant has unique healing and soothing properties. Taken internally, Aloe Vera has been found to regulate digestion, which in turn builds healthy skin from the inside out. Aloe Vera is available as a gel, spray, lotion, juice, cream and in the form of a capsule. Aloe Vera is most commonly found in skin care gels or creams.

Lavender has many uses in skin care that include aiding skin repair, stimulating cell growth, reducing inflammation, preventing scarring and pigmentation, regulating oil production, and reducing pain. Lavender also works as antiseptic or antibacterial agent and is considered an essential oil. Due to its extensive benefits to the skin, lavender is often found in skin care formulated to treat acne prone skin.

Rosemary can be used as an essential oil just like chamomile and lavender. Rosemary and lavender are actually found in the same herbal family.

rosemary skin care

rosemary skin care

Rosemary tones the skin, helping to even out skin tone and texture, while reliving dryness. Rosemary strengthens capillaries and is good to use on aging skin. Rosemary is found in skin care cleansers, toners and creams.

There are many other herbs used in skin care and cosmetics today-most in the form of essential oils or extracts- and all can have different or positive effects on the skin and body. Herbs and oils have been used to heal for many centuries and now are being utilized for safe, natural ways to treat skin conditions and maintain a healthy complexion.

by Tiffany Oney

Chamomile Provides Natural Skin Healing

November 9, 2009 by admin · Leave a Comment 

Chamomile (or camomile) is a common name for several daisy-like plants. The greeks named them “earth-apple-on the ground” for their apple-like scent. There are several varieties of Chamomile - each one used for slightly different purposes or intensities of properties. German or blue chamomile and Roman (English) chamomile, or the “garden” chamomile are the most commonly used.

These two types of chamomile are used for health conditions and are most commonly found in skin care or beauty products. While the two kinds are thought to have similar effects on the body, the German variety is more commonly used in the United States. Chamomile, is one of the oldest of all herbs, dating back to ancient Egyptians. It’s both a pretty flower and an ancient healer. Chamomile has been widely used for children and adults for thousands of years for a variety of health conditions.

Chamomile Provides Natural Skin Healing

Chamomile is an essential addition to the herbal first aid kit. It is a useful herb in many situations. It can relieve anxiety and calm someone down in the event of stress. It can also relieve gastrointestinal upset - after a big meal, or when stress doesn’t mix well with your meal. Chamomile is even an excellent herb to use as compresses for eye problems. Warm two tea bags with chamomile flowers to ease itchy eyes, especially when traveling to different parts of the country and you are not immune to the allergens in that area. It is also used topically for skin conditions and for mouth ulcers resulting from cancer treatment.

How It Is Used

The flowering tops of the chamomile plant are used to make teas, liquid extracts, capsules, or tablets. The herb can also be applied to the skin as a cream or an ointment, or used as a mouth rinse.

Chamomile in Skin Care Products

This versatile herb is also recognized as a natural healing treatment that helps rejuvenate the skin. There are many wonderful natural facial treatments on the market today that incorporate Chamomile as a key ingredient.

To make a quick and easy tea facial, simply apply a paste made from one teaspoon of fine cornmeal mixed with cooled tea to the face, let dry, then gently rub off.

This very gentle skin tonic is ideal to replenish and enrich dry or sensitive skin. Its bactericidal, anti-itching, and antiseptic properties help to refresh the skin and reduce swelling.

Making paste with extra-strong brew and using it as an external wash or part of a hot compress can also help soothe burns, skin rashes, and sores.

Chamomile has excellent anti-inflammatory properties. Chamomile contains an anti-inflammatory compound called alpha bisabolol which helps to soothe itchy, red skin. For this reason, Chamomile along with some other herbs and natural treatments has shown promise as skin treatments for eczema.

According to family physician Dr. Kristie Leong, “Chamomile has been used throughout history to treat various skin conditions and some studies have shown it works as effectively as low dose steroid creams without the side effects. Chamomile oil can be purchased at some health food stores. It needs to be diluted with a carrier oil such as almond oil or jojoba and can then be applied as a skin treatment for eczema. Bathing in warm water containing chamomile flowers may also help to soothe inflammation and itching. Simply make a bath bag using chamomile flowers and float it in a tub of warm bath water.”

For easing skin inflammations and acne, make a strong chamomile tea, and wipe the cooled liquid over your face each morning. This effective daily rinse tones and cleanses.

Essential Oil Usage

Both Roman and German chamomile have excellent calming properties, but Roman chamomile is more effective for irritation, impatience and feeling disagreeable, and has great value in treating PMS and other menstrual and menopausal problems, while German chamomile  is superbly effective on the skin, not only to sooth and calm, but to heal and for tissue regeneration.

Side Effects and Cautions

* There are reports of rare allergic reactions in people who have eaten or come into contact with chamomile products. Reactions include skin rashes, throat swelling, shortness of breath, and anaphylaxis (a life-threatening allergic reaction).
* People are more likely to experience allergic reactions to chamomile if they are allergic to related plants in the daisy family, which includes ragweed, chrysanthemums, marigolds, and daisies.
* Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This helps to ensure coordinated and safe care.

Protein Rich Diet Helps Aging Skin

September 28, 2009 by admin · 1 Comment 

Recent studies report that lack of proteins causes skin-sagging and lack of glow on the skin’s surface. True to the facts,  proteins are very important for the regeneration of skin. They have collagen and keratin that make up of the elastin in the skin. Moreover, you don’t have to eat meat to get your daily source of proteins. For instance, red beans, which are highest in protein content are also highest in antioxidants.

Omega3 fatty acids found in fish and poultry also enhance the hydrating effects of the skin. Therefore, it is important to have a good amount of proteins in our diet, which will detoxify our system naturally, purify our blood and fight the aging process by increasing blood supply to the skin.

Since the American FDA doesn’t always follow organic or other industrialized nation’s standards of health and nutrition. I find it more informative to go to articles and studies conducted in countries where food hormones, pesticides and genetically modified foods are illegal and testing results aren’t skewed in favor of Big Business. Here are some excerpts I found from a great site in Australia.

Overview

Proteins are made up of smaller organic chemicals called amino acids. When proteins are digested, they are broken down into their constituent amino acids before being absorbed into the bloodstream. The body then uses these amino acids to build the kinds of proteins it needs to maintain and repair body tissues such as muscles and organs, and to grow.

There are 20 amino acids. Eleven of these amino acids can be made by the body itself, while the other nine (called Essential Amino Acids) must be obtained from food. The classification of an amino acid as essential or non-essential does not reflect its importance, because all 20 amino acids are necessary for health.

The dietary requirement for protein has two components: total nitrogen requirement (represented by essential plus non-essential amino acids), and requirements for essential amino acids. In assessing dietary protein sources, both need to be considered, as the amount of food protein needed to meet the protein requirement will depend not only on its amount and digestibility, but also on its content of essential amino acids.

Plant Sources of Protein

Plant sources of protein alone can provide adequate amounts of the essential and non-essential amino acids, assuming that dietary protein sources from plants are varied and that total calorie intake is sufficient to meet energy needs. Whole grains, legumes (beans), vegetables, seeds, and nuts, as well as commercial meat alternatives, all contain essential and non-essential amino acids.

Some plant foods are low in one kind of amino acid (e.g. grains are low in lysine), while other plant foods are higher in that amino acid (e.g. legumes are quite high in lysine). So by eating a well balanced diet that contains a variety of foods it is possible to obtain all the amino acids that the body requires. Note that while recent research shows that soy contains all essential amino acids, and is therefore a complete protein source, in my opinion it is preferable to have a varied diet and not depend on one food source to meet a particular dietary need.

The American Dietetic Association and Dietitians of Canada state in their Position Statement on Vegetarian Diets:

“It is the position of the American Dietetic Association and Dietitians of Canada that appropriately planned vegetarian diets are healthful, nutritionally adequate, and provide health benefits in the prevention and treatment of certain diseases… Plant protein can meet requirements when a variety of plant foods is consumed and energy needs are met. Research indicates that an assortment of plant foods eaten over the course of a day can provide all essential amino acids and ensure adequate nitrogen retention and use in healthy adults…”

In the past it was widely believed that in order for vegetarians to obtain adequate amounts of protein, all of the essential amino acids had to be ‘balanced’ at each meal. For example, grains and legumes had to be consumed at the same meal. This is referred to as ‘protein combining’. However, more recent research has indicated that, while consuming a proper mix of amino acids is important, it is not necessary to consume them all at the same meal.

Protein Deficiency

Protein deficiency is rare in Western countries but has wide-ranging effects on the body. Dietary protein deficiency in humans occurs principally in children in the form of kwashiorkor, although a similar syndrome is sometimes seen in severely depleted hospital patients with increased protein catabolism.

Kwashiorkor occurs most commonly in areas of famine, limited food supply, and low levels of education, which can lead to inadequate knowledge of proper diet. Early symptoms of any type of malnutrition are very general and include fatigue, irritability, and lethargy. As protein deprivation continues, growth failure, loss of muscle mass, generalised swelling (oedema), and decreased immunity occur. A large, protuberant belly is common. Skin conditions, such as dermatitis, changes in pigmentation, thinning of hair, and vitiligo (loss of skin colour) can also occur.

Protein deficiency among well-fed vegetarians and vegans is rarely a concern. A protein deficiency may be seen when there is also a calorie deficiency, but in such cases many nutrients would be a concern. The other possible scenario of insufficient protein intake would be where a vegan has a very poor diet that is heavily dependant on fruit or refined junk food such as sugary drinks, pastries and chips.

To read more on proteins and vegetarianism, go to http://www.vnv.org.au

Skin Care Ingredients to Look For

July 28, 2009 by admin · Leave a Comment 

Before we have a discussion of specific ingredients, it’s important to educate ourselves a little bit more on skin itself and what makes a product good or poor. Your skin is the largest organ of the body. Anything you put on it can be easily absorbed through the pores. When you use skin care products, they are typically applied all over the face, neck, and body. This covers a lot of surface area and, therefore, a great deal of chemical absorption occurs.

The biggest reason our skin, whether on the face or the rest of the body, develops lines and/or starts to sag, is that the collagen and elastin in our skin begins to break down. Collagen is a protein that is fibrous in nature. What makes collagen different from other kinds of protein is that it possesses great tensile strength, which means, among other things, it provides firmness to the skin.

You don’t need to be a scientist, therefore, to understand that as collagen breaks down due to aging, the firmness of our skin becomes…well, less firm. Wrinkles appear and skin starts to sag.

Elastin, too, is a protein that helps skin stay “flexible” and firm. If your skin is stretched, elastin is the protein that helps it return to its original position.

What all of this means for you as a consumer is you do want to avoid buying products that are nothing more than wrinkle or fine line ‘fillers.’ Some creams will give the appearance of plumper fuller skin while it still sits on the surface, but once absorbed or removed, the illusion is gone. Want you want to look for is a product that actually stimulates new collagen and elastin production in your skin. If you achieve this, you will, in reality, begin to turn back the clock.

Unfortunately, some cosmetic manufacturers will include some great ‘active ingredients’ while filling the majority of the product with inferior filler. Because these active ingredients are beneficial for the skin, they include just enough to be allowed to legally list them on the product label. This way, the typical consumer thinks they are getting a great product of high-quality. But, because these ingredients are expensive, and because, many well known companies spend much of their budget on marketing, the amount of these ‘active ingredients’ is limited to have any real benefit for your skin.

So, when choosing a skin care product, it’s not just about selecting one with good ingredients; it’s also about choosing one with a high concentration of these good ingredients.

•    Collagen

After the brief review of the importance of collagen, you would think that buying a product with collagen in it would be a great thing. And the marketers who sell products that contain collagen know this. But, again sadly, collagen molecules are much too large to penetrate into the skin when applied topically and there presence in a beauty product has no effect whatsoever. To be of any benefit, you must purchase a product with ingredients that have been shown to stimulate your body’s own collagen production.

•    Phytessence Wakame

Phytessence Wakame is an exotic kelp, native to the Japanese Sea. It works by blocking a harmful enzyme in your body called hyaluronidase. Hyaluronidase breaks down hyaluronic acid in your skin. Without hyaluronic acid, the elastin and collagen fibers lose their “glue,” which leads to a loss of youthful appearance and dark eye circles. Hyaluronan is a major component of skin, where it is involved in tissue repair.

•    CoQ10

If you look at the ingredient list for some of the better skin care products, you’ll often see CoQ10 listed. CoQ10 is short for Coenzyme Q10, so you may also see it listed this way. CoQ10 is a vitamin like substance that is found in all of our body’s cells and is very important for healthy skin. CoQ10 is a powerful antioxidant. A lot of skin damage and aging comes from free radicals wreaking havoc in our body’s cells. CoQ10’s antioxidant ability can counter these free radicals before damage occurs.

Unfortunately, like many other vital substances, as we age, the amount of CoQ10 in our bodies becomes depleted.

Although CoQ10 is a great ingredient, not all forms are equal. One in particular stands head and shoulders above the rest. This version of it is called Nano-Lipobelle H-EQ10.Most of the CoQ10 you buy in a typical skin care products are not readily usable when applied topically to the skin.

•    Nano-Lipobelle H-EQ10, on the other hand, is a special nano-emulsion form of CoQ10, which penetrates far down into the skin, thereby providing much greater benefits for skin health. In fact, Nano-Lipobelle H-EQ10 has been shown to penetrate seven layers deep into the skin, making it extremely effective at gobbling up free radicals in your skin. The result is a powerful anti-wrinkle effect.

New Risk Variant For Atopic Dermatitis Identified

April 19, 2009 by admin · Leave a Comment 

Science Daily (Apr. 14, 2009) — Scientists of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité – University Medical School, Berlin, Germany, in collaboration with researchers from the Klinikum rechts der Isar of Technical University Munich and Christian Albrecht University, Kiel, have identified a gene variant on chromosome 11 that is associated with an increased risk of atopic dermatitis.
See also:

In a large genome-wide association study the researchers scanned the genomes of more than 9600 participants from Germany, Poland and the Czech Republic. “Our findings cast new light on the pathogenesis of the disease,” said Professor Young-Ae Lee (Charité / MDC). The pediatrician-researcher and her collaborators hope the study will lead to a new approach to targeted therapy for this chronic skin disorder.

More and more people suffer from atopic dermatitis, which is also known as atopic or infantile eczema. Atopic dermatitis is a chronic (long-lasting) inflammatory skin disease that typically affects the large flexures such as the bend of the elbows or the back of the knees. Patients suffer from recurrent flares of intense itching, dryness and redness of the skin, with weeping of clear fluid in the acute stage, and skin thickening (lichenification) in the chronic stage. Along with hay fever and asthma, atopic dermatitis is one of the most common allergic disorders. In the industrialized countries about 15 percent of young children are affected.

Atopic dermatitis is typically the first clinical manifestation of allergic disease. In most cases atopic dermatitis appears within the first few years of life. For the majority of affected children this marks the beginning of an “allergic career”, which in later years evolves into hay fever or asthma. Just what triggers the outbreak of atopic dermatitis is not yet fully understood. However, epidemiological studies indicate that the genetic contribution is substantial.

For that reason, of the total of 9600 study participants, the scientists decided to scrutinize the genomes of 3011 individuals more closely. These included children and adults with atopic dermatitis, healthy controls, as well as entire families in which at least two children have atopic dermatitis. The researchers scanned the entire genome, searching for genetic variants that are especially common in atopic dermatitis patients.

The study demonstrates that several genes are involved in the pathogenesis of atopic dermatitis. Most importantly, the researchers identified a variant on chromosome 11 that is particularly common in the patients with atopic dermatitis. This variant is located in a region containing the gene C11orf30 which encodes the protein EMSY. The scientists suspect that a mutation in this gene is associated with atopic dermatitis. However, the exact role of EMSY in atopic dermatitis still needs to be investigated.

Same variant also a risk factor for Crohn’s disease

The same variant on chromosome 11 is also common in patients with Crohn’s disease, a chronic inflammatory disease of the gastrointestinal tract. Scientists therefore suspect that this variant on chromosome 11 will unravel a novel common disease mechanism that can lead to chronic inflammation of various organs. The variant is very widespread: in Europe, 36 percent of the population are carriers. Now the MDC and Charité scientists want to decipher the exact function of EMSY in atopic dermatitis.

Furthermore, the scientists show that other previously unknown variants in genes related to the outermost skin layer (epidermis) increase the risk for the disease. The researchers hope that their findings will contribute to improved treatment for atopic dermatitis sufferers. “To develop a targeted intervention,” they explained, “we must first fully understand the underlying disease mechanism.”

Journal reference:

1. Esparza-Gordillo et al. A common variant on chromosome 11q13 is associated with atopic dermatitis. Nature Genetics, 2009; DOI: 10.1038/ng.347

Adapted from materials provided by Helmholtz Association of German Research Centres, via EurekAlert!, a service of AAAS.

Supplements for Your Skin

April 18, 2009 by admin · Leave a Comment 

Dry skin recommendations and supplements that can help your skin

Dry skin responds best to climates with high humidity and hates cold, dry and windy climates. Indoor heating and air-conditioning can also be drying to skin. If you live in a dry climate, try to use a humidifier to add moisture to the air. There are many affordable varieties available on the market or for re-sale today.
Don’t steam your face or use excessive steaming facials because steaming is actually more drying than hydrating. Likewise, avoid steam rooms, swimming pools, chlorinated hot tubs and overly hot baths. Avoid those old-fashioned recommendations to put your face under a towel over a pot of boiling water. Not only will this lead to excessive drying, it can also cause broken capillaries or blood veins along the fragile skin of the cheeks and nose.

If your skin tends to be dry, and tight or wrinkled and sun spotted, avoid excessive sun, exposure or hot wax facial treatments, hair sprays and hair dyes that can dry your skin and provoke inflammation leading to dark spots.

Hormone replacement therapy can help to lessen skin dryness after Menopause though it will increase age spots due to new hormones stimulating pigment production. It may help prevent the wrinkles that quickly occur after menopause Consult with your doctor with your family health history to make an informed decision on HRT.

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